Description
Human Proteasome Subunit Alpha Type 2 (PSMA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Proteasome Subunit Alpha Type 2 (PSMA2) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit